Ketamine Pharmacodynamics

CNS

blocks thalamic - cortex transmission
‘dissociative anaesthesia’
increased CBF (raised CO2)
hallucinations and confusion in 24-34% adults
more common with atropine, droperidol
may be suppressed by:
midazolam 0.05 mg/Kg
thiopentone 2 mg/Kg

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Friday, 19 September 2008 06:33:58